diff --git a/vector/src/main/java/im/vector/app/core/extensions/ViewExtensions.kt b/vector/src/main/java/im/vector/app/core/extensions/ViewExtensions.kt
index 156809d5ad..55ad5294d9 100644
--- a/vector/src/main/java/im/vector/app/core/extensions/ViewExtensions.kt
+++ b/vector/src/main/java/im/vector/app/core/extensions/ViewExtensions.kt
@@ -20,6 +20,8 @@ import android.graphics.drawable.Drawable
 import android.text.InputType
 import android.view.View
 import android.view.ViewGroup
+import android.view.accessibility.AccessibilityEvent
+import android.view.accessibility.AccessibilityNodeInfo
 import android.widget.EditText
 import android.widget.ImageView
 import androidx.annotation.AttrRes
@@ -28,6 +30,7 @@ import androidx.annotation.DrawableRes
 import androidx.appcompat.widget.SearchView
 import androidx.core.content.ContextCompat
 import androidx.core.graphics.drawable.DrawableCompat
+import androidx.core.view.ViewCompat
 import androidx.core.view.isVisible
 import androidx.transition.ChangeBounds
 import androidx.transition.Fade
@@ -97,6 +100,14 @@ fun View.setAttributeBackground(@AttrRes attributeId: Int) {
     setBackgroundResource(attribute.resourceId)
 }
 
+/**
+ * Inspired from https://stackoverflow.com/a/64597532/1472514. Safer to call the 2 available API.
+ */
+fun View.giveAccessibilityFocus() {
+    ViewCompat.performAccessibilityAction(this, AccessibilityNodeInfo.ACTION_ACCESSIBILITY_FOCUS, null)
+    sendAccessibilityEvent(AccessibilityEvent.TYPE_VIEW_SELECTED)
+}
+
 fun ViewGroup.animateLayoutChange(animationDuration: Long, transitionComplete: (() -> Unit)? = null) {
     val transition = TransitionSet().apply {
         ordering = TransitionSet.ORDERING_SEQUENTIAL
diff --git a/vector/src/main/java/im/vector/app/features/popup/PopupAlertManager.kt b/vector/src/main/java/im/vector/app/features/popup/PopupAlertManager.kt
index 29aa623c9b..02275c933e 100644
--- a/vector/src/main/java/im/vector/app/features/popup/PopupAlertManager.kt
+++ b/vector/src/main/java/im/vector/app/features/popup/PopupAlertManager.kt
@@ -24,6 +24,7 @@ import android.view.WindowInsetsController.APPEARANCE_LIGHT_STATUS_BARS
 import androidx.core.view.ViewCompat
 import com.tapadoo.alerter.Alerter
 import im.vector.app.R
+import im.vector.app.core.extensions.giveAccessibilityFocus
 import im.vector.app.core.platform.VectorBaseActivity
 import im.vector.app.core.resources.StringProvider
 import im.vector.app.core.utils.isAnimationEnabled
@@ -286,7 +287,7 @@ class PopupAlertManager @Inject constructor(
                     currentIsDismissed()
                 }
                 .setOnShowListener {
-                    handleAccessibility(activity)
+                    handleAccessibility(activity, animate)
                 }
                 .enableSwipeToDismiss()
                 .enableInfiniteDuration(true)
@@ -304,7 +305,7 @@ class PopupAlertManager @Inject constructor(
     }
 
     /* a11y */
-    private fun handleAccessibility(activity: Activity) {
+    private fun handleAccessibility(activity: Activity, giveFocus: Boolean) {
         activity.window.decorView.findViewById<View>(R.id.llAlertBackground)?.let { alertView ->
             alertView.importantForAccessibility = View.IMPORTANT_FOR_ACCESSIBILITY_YES
 
@@ -318,6 +319,11 @@ class PopupAlertManager @Inject constructor(
                 Alerter.hide()
                 true
             }
+
+            // And give focus to the alert right now, only for first display, i.e. when there is an animation.
+            if (giveFocus) {
+                alertView.giveAccessibilityFocus()
+            }
         }
     }